Phylo-VISTA: An Interactive Visualization Tool for Multiple DNA Sequence Alignments
نویسندگان
چکیده
We have developed Phylo-VISTA (Shah et al., 2003), an interactive software tool for analyzing multiple alignments by visualizing a similarity measure for DNA sequences of multiple species. The complexity of visual presentation is effectively organized using a framework based upon inter-species phylogenetic relationships. The phylogenetic organization supports rapid, user-guided inter-species comparison. To aid in navigation through large sequence datasets, Phylo-VISTA provides a user with the ability to select and view data at varying resolutions. The combination of multi-resolution data visualization and analysis, combined with the phylogenetic framework for inter-species comparison, produces a highly flexible and powerful tool for visual data analysis of multiple sequence alignments. Availability http://www-gsd.lbl.gov/phylovista/
منابع مشابه
Phylo-VISTA: interactive visualization of multiple DNA sequence alignments
MOTIVATION The power of multi-sequence comparison for biological discovery is well established. The need for new capabilities to visualize and compare cross-species alignment data is intensified by the growing number of genomic sequence datasets being generated for an ever-increasing number of organisms. To be efficient these visualization algorithms must support the ability to accommodate cons...
متن کاملxREI: a phylo-grammar visualization webserver
Phylo-grammars, probabilistic models combining Markov chain substitution models with stochastic grammars, are powerful models for annotating structured features in multiple sequence alignments and analyzing the evolution of those features. In the past, these methods have been cumbersome to implement and modify. xrate provides means for the rapid development of phylo-grammars (using a simple fil...
متن کاملVISTA : visualizing global DNA sequence alignments of arbitrary length
SUMMARY VISTA is a program for visualizing global DNA sequence alignments of arbitrary length. It has a clean output, allowing for easy identification of similarity, and is easily configurable, enabling the visualization of alignments of various lengths at different levels of resolution. It is currently available on the web, thus allowing for easy access by all researchers. AVAILABILITY VISTA...
متن کاملPhylo-mLogo: An interactive multiple-logo visualization tool for large-number sequence alignments
When aligning several hundreds or thousands of sequences, such as HIVs, dengue virus, and influenza viruses, to reconstruct the epidemiological history or to understand the mechanisms of epidemic virus evolution, how to analyze and visualize the large-number alignment results has become a new challenge for computational biologists. Although there are several tools available for visualization of...
متن کاملMultiple whole genome alignments and novel biomedical applications at the VISTA portal
The VISTA portal for comparative genomics is designed to give biomedical scientists a unified set of tools to lead them from the raw DNA sequences through the alignment and annotation to the visualization of the results. The VISTA portal also hosts the alignments of a number of genomes computed by our group, allowing users to study the regions of their interest without having to manually downlo...
متن کامل